The largest emerging market in healthcare is forming right now.
Early infrastructure wins everything.

If you're looking at where behavioral medicine, natural science, and artificial intelligence converge — you're looking at the right company.

The Market

The largest undertreated crisis in modern medicine.

$380B
Global behavioral health market today
Projected $620B by 2030
1 in 5
Adults living with a diagnosable mental health condition
Most never receive adequate care
400%
Increase in antidepressant prescriptions over two decades
Outcomes have not kept pace
The Natural Medicine Opportunity
$6.9B
Psychedelic therapeutics market today
Projected $11.1B by 2030
10+
US states with active natural medicine programs or funded legislation
As of May 2026 — expanding monthly
$100B+
Projected global psilocybin-assisted therapy market
Within a decade — multiple analyst projections

Oregon's first year of legal psilocybin services generated over $10M in revenue — with waitlists overflowing.

We started with a simple observation: the most important moments in someone's healing journey almost never happen in a therapist's office. They happen at 2am when the anxiety won't stop. They happen on a Tuesday when no one is watching. They happen in the 167 hours between appointments that nobody owned.

The infrastructure supporting behavioral health has not meaningfully changed in fifty years. Appointments are still weekly. Tools between sessions still don't exist at scale. The continuity of care that produces lasting outcomes is still missing.

And the conditions demanding that continuity are growing faster than any existing system can address. PTSD affects 13 million Americans — with veterans and first responders carrying a disproportionate burden that weekly appointments alone have never resolved. Traumatic brain injury and CTE are reaching epidemic levels in contact sports, military service, and beyond, with no daily intervention tools built specifically for them. Early-stage neurodegeneration and cognitive decline — conditions where daily training, sleep, and stress regulation are among the most evidence-supported interventions available — are projected to affect 1 in 3 people over 65 within a decade. These are not niche populations. They are the fastest-growing patient categories in modern medicine, and they share one thing in common: the gap between what the science says works and what people can actually access every single day.

The Moment

The science arrived.
The infrastructure didn't.
Until now.

Something significant is happening in medicine. Psilocybin has received FDA Breakthrough Therapy designation. Ketamine-assisted therapy is producing outcomes that no prior treatment has matched. The clinical evidence is no longer emerging — it has arrived.

More than 10 states now have active natural medicine legislation, operational programs, or funded research mandates signed into law — with more advancing through legislatures and ballot processes every month. What began with Oregon and Colorado has become a nationwide infrastructure movement.

What hasn't existed until now is the infrastructure to support it responsibly, at scale, connected to the digital tools people need between sessions. That is what we built.

Operational2026 LegislationAdvancing
Oregon — Psilocybin Services Program · Operational since 2023
Colorado — Natural Medicine Health Act · Operational · Psilocybin, DMT, Ibogaine, Mescaline
New Mexico — Medical Psilocybin Access · First Legislature-Passed Program
FDA Breakthrough Therapy Designation — Psilocybin
Washington State — Psilocybin Therapy Pilot Program · University-Based
New Jersey — $6M Psychedelic Research Initiative · Signed January 2026
Texas — $50M Ibogaine Research Mandate · Active
Utah — Veteran Psychedelic-Assisted Therapy Bill · Signed March 2026
Mississippi — Ibogaine Research Bill · Signed March 2026
Alaska — Natural Medicine Ballot Initiative · Signature Gathering Active
South Dakota — Trigger Law Advancing · 2026 Session
West Virginia — Trigger Law Advancing · 2026 Session

10+ states with active programs, funded research, or advancing legislation — as of May 2026

Who We Are

The clinical infrastructure behavioral health has been waiting for.

We're a Colorado company working at the edge of natural medicine, behavioral AI, and cognitive science — and we're doing it differently than anyone else.

We hold cultivation, manufacturing, and healing center licenses under Colorado's Natural Medicine Health Act. That means we control the medicine, the facility, the clinical team, and the technology platform that ties it all together. No middlemen. No gaps. One continuous experience from the first session to the last.

Our flagship platform, Bloome, is a behavioral intelligence platform in final pre-launch testing — combining adaptive AI therapy, cognitive training, hormone health, natural medicine companion tools, and a full clinician dashboard connected by a living psychological model that learns from you every single day.

We are the only company in this space that owns the medicine, the facility, the therapists, and the technology platform that connects them.

Bloome is currently in active patent exploration across more than 20 novel applications — spanning behavioral AI methodology, adaptive therapeutic protocols, cognitive training systems, and natural medicine companion technology. We are not just building a platform. We are building intellectual property that defines a category.

20+ Novel Patent Applications · In Review
Third State Technology
Bloome — behavioral intelligence platform
Third State Inc.
Licensed natural medicine vertical — cultivation, manufacturing, and healing center
Third State Distribution
Vybe — functional mood enhancement consumer brand
Get in Touch

Interested in the future of behavioral health?

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This page does not constitute an offer to sell or solicitation to buy securities. Any investment opportunity will be presented only through official offering documents to qualified investors. Third State Holdings, Inc. · Delaware · Patent Pending